平台概况
浙江大学国际健康医学研究院公共技术平台成立于2022年,由公共实验平台、公共大型仪器平台和生物样本库组成,隶属于浙江大学医学院附属第四医院医学研究中心。其宗旨是为浙江大学国际健康医学研究院、浙江大学医学院附属第四医院、浙江大学“一带一路”国际医学院的科研教学工作提供优质、高效和专业的技术服务。服务内容包括:仪器分析技术、实验操作技术、生物样本管理、大型仪器使用培训等。
公共技术平台定位明确,空间规划及布局合理。公共大型仪器平台位于研究院18楼,实验室面积1700多平方,包含成像平台、蛋白质平台、理化测试平台、流式平台、生化平台、组织形态学平台等分平台,平台拥有总价值约3500万元的仪器近40台,其中包括流式分析仪、流式分选仪、转盘式共聚焦、高内涵、海马组织代谢仪、高效液相色谱、蛋白纯化仪等大型仪器。设备配置符合现代生物医学研究需求,通用性好,共享程度高,配有专业的实验技术指导老师和先进高效的在线预约共享信息系统。
公共实验平台位于研究院14楼,实验室面积1700多平方,现有实验设备50多台,可以开展细胞和分子生物学相关实验操作场地,为“三院一体”员工的科学研究提供开放实验室。
生物样本库筹建于2018年,位于浙大四院负一楼。样本库目前配置超低温冰箱8台(-80℃)、液氮罐2台、液氮转运箱1台、低温标签打印机1台、离心机2台等仪器,样本存储量为15万份。2023年,我中心将申请在原有空间的基础上扩建至100-150平左右,进行合理规划和改造,并新增超低温冰箱和升级信息系统,进而满足生物安全的要求,规范医院科研工作者样本存储的科研需求并申请人类遗传保藏审批和CNAS-AL21生物样本库质量和能力认可资质。
The Public Technology Platform established in 2022 is affiliated to Medical Research Center of Zhejiang University International Institutes of Medicine, and composed of Public Experiment Platform, Public Instrument Platform and Biobank. The purpose the Public Technology Platform is to provide high-quality, efficient and professional technical services for Zhejiang University International Institutes of Medicine, Fourth Affiliated Hospital of Zhejiang University School of Medicine and Zhejiang University International School of Medicine. The services include instrument training, experimental operation, biological samples management, etc.
The Public Instrument Platform is located on the 18th floor with 1700 square meters in Zhejiang University International Institutes of Medicine, and including Imaging Platform, Protein Analysis Platform, Physical and Chemical Analysis Platform, Flow Cytometry Platform, Biochemical Platform, Histomorphological Platform, etc. The instruments valued around 35 million yuan include BD Fortessa Flow Cytometer, BD FACSAria™ III Cell Sorter, Spinning-disk Confocal Microscope, High Content Screening System, Seahorse XFe96, HPLC and Cytiva(GE) AKTATM pure, etc. There are professional experimental technology instructors for guidance and efficient online reservation sharing information system to meet the needs of all researcher and students.
The Public Experiment Platform is located on the 14th floor with 1700 square meters of laboratory area, and equipped with more than 50 experimental instruments. It is an open laboratory for the scientific researchers to conduct cell and molecular biological experiments.
The Biobank established in 2018 is located on the 1st basement floor of Fourth Affiliated Hospital of Zhejiang University School of Medicine. Currently, the maximum sample storage capacity of Biobank is 150,000 and it is equipped with - 80 ℃ ultra-low temperature refrigerators, liquid nitrogen tanks and liquid nitrogen transfer boxes, etc. The Biobank will be expanded in space and instruments and the information system will be upgraded to meet the needs of biosafety requirements and sample storage for hospital researchers. We will strive to obtain the approval of human genetic preservation and CNAS-AL21 biological sample bank quality and capacity accreditation in 2023.